Olink Explorer >5400

Requirements: 2.0 BACKGROUND Our lab studies the role of inflammation/innate resistance and commensal microbiota in carcinogenesis, cancer progression and therapy of cancer. The following product features/characteristics are required for this requirement: Protein Coverage - Measures ~5,400+ human proteins simultaneously in a single workflow. Technology - Uses Proximity Extension Assay (PEA) with dual antibody recognition coupled to DNA barcoding and next-generation sequencing (NGS) readout. Sample input – requires only 2 ul of plasma, serum, and other sample types Specificity - Reported 99.5% specificity with negligible cross-reactivity due to dual-recognition antibody design. Dynamic Range - Approximately 10 orders of magnitude (fg/mL to mg/mL), enabling detection of both low- and high-abundance proteins. Key strengths Very broad proteome coverage while maintaining antibody-based specificity. Excellent sensitivity for low-abundance circulating proteins (especially cytokines and signaling proteins). Extremely low sample-volume requirement. Highly standardized platform, making it attractive for epidemiology and multi-omics studies.

• NAICS541380
• PSCQ301

• Requirement 7.docx

  .docx17 KBNot yet available

• John Burton
  burtonjo@mail.nih.gov